Wondering what would be the best reading method

Currently, I am reading Murakami Haruki's Hard Boiled Wonderland – End of the World. I understand the context pretty well but on a page, I may not know 2-3 kanji on average. However, even skipping past them, I am able to understand the context.
For example, 頭骨(I can infer it is the something about head brain). But, also there are some kanji like ,立派 which I had to search up but I could skip because I know that it means great from the context around it.

My question is, should I take time to search up the kanji or should I just skip past it (and save time) and just understand the meaning. If I skip past it, I may not know how to read it when it comes up and maybe distort the meaning.

by SerenityFlakes